Gardasil (HPV quadrivalent vaccine) and Gardasil 9 (HPV 9-valent vaccine) are used in both females and males. Another form of HPV vaccine (Cervarix) is used only in females. This medication guide provides information only for Gardasil (HPV quadrivalent vaccine).

Gardasil (HPV) can cause genital warts, cancer of the cervix, anal cancer, and various cancers of the vulva or vagina.

Gardasil is used in girls and young women ages 9 through 26 to prevent cervical/vaginal/anal cancers caused by certain types of HPV.

Gardasil is also used in boys and young men ages 9 through 26 to prevent anal cancer or genital warts caused by certain types of HPV.

You may receive Gardasil even if you have already had genital warts, or had a positive HPV test or abnormal pap smear in the past. However, this vaccine will not treat active genital warts or HPV-related cancers, and it will not cure HPV infection.

Gardasil only prevents diseases caused by HPV types 6, 11, 16, and 18. It will not prevent diseases caused by other types of HPV.

The Centers for Disease Control and Prevention (CDC) recommends HPV vaccine for all boys and girls ages 11 or 12 years old. The vaccine is also recommended in teenage boys and girls who have not already received the vaccine or have not completed all booster shots.

Like any vaccine, the Gardasil may not provide protection from disease in every person.

Each 0.5 mL dose contains human papilloma virus (HPV) 6 L1 protein approximately 20 mcg, HPV 11 L1 protein 40 mcg, HPV 16 L1 protein 40 mcg and HPV 18 L1 protein 20 mcg.

Gardasil also contains the following inactive ingredients: Aluminum approximately 225 mcg (as amorphous aluminum hydroxyphosphate sulfate adjuvant), sodium chloride 9.56 mg, L-histidine 0.78 mg, polysorbate 80 50 mcg, sodium borate 35 mcg and water for injection. Gardasil does not contain a preservative or antibiotics.

Gardasil is a sterile preparation for IM administration.



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