what is sofosbuvir

buy sofosbuvir are antiviral medications that prevent hepatitis C virus (HCV) cells from multiplying in your body.

Harvoni is a combination medicine used to treat hepatitis C in adults.

where to buy sofosbuvir:

Harvoni may also be used for purposes not listed in this medication guide.

Harvoni is a 2-drug fixed-dose combination product containing Ledipasvir (Harvoni) 90 mg and Sofosbuvir (Harvoni) 400 mg in a single tablet, for oral administration.

Each tablet contains Ledipasvir (Harvoni) 90 mg and Sofosbuvir (Harvoni) 400 mg.

It also includes the following excipients: Colloidal silicon dioxide, copovidone, croscarmellose sodium, lactose monohydrate, magnesium stearate and microcrystalline cellulose. Film-Coating: FD&C yellow no. 6/sunset yellow FCF aluminum lake, polyethylene glycol, polyvinyl alcohol, talc and titanium dioxide.

Ledispavir is a hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor and Sofosbuvir (Harvoni) is a nucleotide analog inhibitor of HCV NS5B polymerase.

Ledipasvir (Harvoni) is methyl [(2S)-1-{(6S)-6-[5-(9,9-difluoro-7-{2-[(1R,3S,4S)-2-{(2S)-2-[(methoxycarbonyl)amino]3 methylbutanoyl}-2-azabicyclo(2.2.1)hept-3-yl)-1H-benzimidazol-6-yl}-9H-fluoren-2-yl)-1H-imidazol-2-yl]-5-azaspiro(2.4)hept-5-yl}-3-methyl-1-oxobutan-2-yl]carbamate. It has a molecular formula of C49H54F2N8Oand a molecular weight of 889.

Ledipasvir (Harvoni) is practically insoluble (<0.1 mg/mL) across the pH range of 3-7.5 and is slightly soluble below pH 2.3 (1.1 mg/mL).

Sofosbuvir (Harvoni) is (S)-Isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy (phenoxy)phosphorylamino)propanoate. It has a molecular formula of C22H29FN3O9P and a molecular weight of 529.45.

Sofosbuvir (Harvoni) is a white to off-white crystalline solid with a solubility of ≥2 mg/mL across the pH range of 2-7.7 at 37°C and is slightly soluble in water.

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